Lymphangiogenesis and cancer metastasis
Identifieur interne : 006204 ( Main/Exploration ); précédent : 006203; suivant : 006205Lymphangiogenesis and cancer metastasis
Auteurs : Viviane Mumprecht ; Michael DetmarSource :
- Journal of Cellular and Molecular Medicine [ 1582-1838 ] ; 2009.
Abstract
Metastasis is a characteristic trait of most tumour types and the cause for the majority of cancer deaths. Many tumour types, including melanoma and breast and prostate cancers, first metastasize
Url:
DOI: 10.1111/j.1582-4934.2009.00834.x
PubMed: 19583813
PubMed Central: 3572232
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lymphangiogenesis and cancer metastasis</title><author><name sortKey="Mumprecht, Viviane" sort="Mumprecht, Viviane" uniqKey="Mumprecht V" first="Viviane" last="Mumprecht">Viviane Mumprecht</name></author><author><name sortKey="Detmar, Michael" sort="Detmar, Michael" uniqKey="Detmar M" first="Michael" last="Detmar">Michael Detmar</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">19583813</idno><idno type="pmc">3572232</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572232</idno><idno type="RBID">PMC:3572232</idno><idno type="doi">10.1111/j.1582-4934.2009.00834.x</idno><date when="2009">2009</date><idno type="wicri:Area/Pmc/Corpus">000524</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000524</idno><idno type="wicri:Area/Pmc/Curation">000524</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000524</idno><idno type="wicri:Area/Pmc/Checkpoint">003683</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">003683</idno><idno type="wicri:Area/Ncbi/Merge">003500</idno><idno type="wicri:Area/Ncbi/Curation">003500</idno><idno type="wicri:Area/Ncbi/Checkpoint">003500</idno><idno type="wicri:doubleKey">1582-1838:2009:Mumprecht V:lymphangiogenesis:and:cancer</idno><idno type="wicri:Area/Main/Merge">006279</idno><idno type="wicri:Area/Main/Curation">006204</idno><idno type="wicri:Area/Main/Exploration">006204</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Lymphangiogenesis and cancer metastasis</title><author><name sortKey="Mumprecht, Viviane" sort="Mumprecht, Viviane" uniqKey="Mumprecht V" first="Viviane" last="Mumprecht">Viviane Mumprecht</name></author><author><name sortKey="Detmar, Michael" sort="Detmar, Michael" uniqKey="Detmar M" first="Michael" last="Detmar">Michael Detmar</name></author></analytic><series><title level="j">Journal of Cellular and Molecular Medicine</title><idno type="ISSN">1582-1838</idno><idno type="eISSN">1582-4934</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Metastasis is a characteristic trait of most tumour types and the cause for the majority of cancer deaths. Many tumour types, including melanoma and breast and prostate cancers, first metastasize <italic>via</italic> lymphatic vessels to their regional lymph nodes. Although the connection between lymph node metastases and shorter survival times of patients was made decades ago, the active involvement of the lymphatic system in cancer, metastasis has been unravelled only recently, after molecular markers of lymphatic vessels were identified. A growing body of evidence indicates that tumour-induced lymphangiogenesis is a predictive indicator of metastasis to lymph nodes and might also be a target for prevention of metastasis. This article reviews the current understanding of lymphangiogenesis in cancer anti-lymphangiogenic strategies for prevention and therapy of metastatic disease, quantification of lymphangiogenesis for the prognosis and diagnosis of metastasis and <italic>in vivo</italic> imaging technologies for the assessment of lymphatic vessels, drainage and lymph nodes.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Cueni, Ln" uniqKey="Cueni L">LN Cueni</name></author><author><name sortKey="Detmar, M" uniqKey="Detmar M">M Detmar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gerli, R" uniqKey="Gerli R">R Gerli</name></author><author><name sortKey="Solito, R" uniqKey="Solito R">R Solito</name></author><author><name sortKey="Weber, E" uniqKey="Weber E">E Weber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baluk, P" uniqKey="Baluk P">P Baluk</name></author><author><name 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uniqKey="Kono Y">Y Kono</name></author><author><name sortKey="Corbeil, J" uniqKey="Corbeil J">J Corbeil</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoffman, Jm" uniqKey="Hoffman J">JM Hoffman</name></author><author><name sortKey="Gambhir, Ss" uniqKey="Gambhir S">SS Gambhir</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cserni, G" uniqKey="Cserni G">G Cserni</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jaffer, Fa" uniqKey="Jaffer F">FA Jaffer</name></author><author><name sortKey="Weissleder, R" uniqKey="Weissleder R">R Weissleder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Harisinghani, Mg" uniqKey="Harisinghani M">MG Harisinghani</name></author><author><name sortKey="Barentsz, J" uniqKey="Barentsz J">J Barentsz</name></author><author><name sortKey="Hahn, Pf" uniqKey="Hahn P">PF Hahn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zudaire, E" uniqKey="Zudaire E">E Zudaire</name></author><author><name sortKey="Martinez, A" uniqKey="Martinez A">A Martinez</name></author><author><name sortKey="Cuttitta, F" uniqKey="Cuttitta F">F Cuttitta</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Detmar, Michael" sort="Detmar, Michael" uniqKey="Detmar M" first="Michael" last="Detmar">Michael Detmar</name><name sortKey="Mumprecht, Viviane" sort="Mumprecht, Viviane" uniqKey="Mumprecht V" first="Viviane" last="Mumprecht">Viviane Mumprecht</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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